The Eukaryote Genome in Development and Evolution

The Eukaryote Genome in Development and Evolution

Author: John Bernard

Publisher: Springer Science & Business Media

ISBN: 9789401159913

Category: Science

Page: 416

View: 324

'The mind unlearns with difficulty what has long been impressed upon it. ' Seneca Reductionism, is, without question, the most successful analytical approach available to the experimental scientist. With the advent of techniques for cloning and sequencing DNA, and the development of a variety of molecular probes for localizing macromolecules in cells and tissues, the biologist now has available the most powerful reductionist tools ever invented. The application of these new technologies has led to a veritable explosion of facts regarding the types and organization of nucleotide sequences present in the genomes of eukaryotes. These data offer a level of precision and predictability which is unparalleled in biology. Recombinant DNA techniques were initially developed to gather information about the structure and organization of the DNA sequences within a genome. The power and potential of these techniques, however, extend far beyond simple data collection of this kind. In an attempt to use the new technology as a basis for analyzing development and evolution, attention was first focused on the topic of gene regulation, an approach that had proven so successful in prokaryotes. It is now clear that this has not been an adequate approach. Lewin (1984) has quoted Brenner as stating 'at the beginning it was said that the answer to the understanding of development was going to come from a knowledge of the molecular mechanisms of gene control. I doubt whether anyone believes this any more.

The Eukaryote Genome in Development and Evolution
Language: en
Pages: 416
Authors: John Bernard
Categories: Science
Type: BOOK - Published: 2012-12-06 - Publisher: Springer Science & Business Media

'The mind unlearns with difficulty what has long been impressed upon it. ' Seneca Reductionism, is, without question, the most successful analytical approach available to the experimental scientist. With the advent of techniques for cloning and sequencing DNA, and the development of a variety of molecular probes for localizing macromolecules
Genetics and Genomics of the Triticeae
Language: en
Pages: 700
Authors: Catherine Feuillet, Gary J. Muehlbauer
Categories: Science
Type: BOOK - Published: 2009-06-10 - Publisher: Springer Science & Business Media

Sequencing of the model plant genomes such as those of A. thaliana and rice has revolutionized our understanding of plant biology but it has yet to translate into the improvement of major crop species such as maize, wheat, or barley. Moreover, the comparative genomic studies in cereals that have been
Genome Analysis in Eukaryotes
Language: en
Pages: 255
Authors: Rabindra N. Chatterjee, Lucas Sanchez
Categories: Science
Type: BOOK - Published: 2013-03-09 - Publisher: Springer Science & Business Media

During the last decades a breakthrough in the understanding of the mechanisms controlling development has been achieved. This has been possible, in great part, by the use of various experimental approaches. This book focuses on topics concerning some of the processes involved in development, the main emphasis being on the
Code Biology
Language: en
Pages: 224
Authors: Marcello Barbieri
Categories: Science
Type: BOOK - Published: 2015-02-02 - Publisher: Springer

This book is the study of all codes of life with the standard methods of science. The genetic code and the codes of culture have been known for a long time and represent the historical foundation of this book. What is really new in this field is the study of
Genetics, Development, and Evolution
Language: en
Pages: 361
Authors: J. Perry Gustafson, G. Ledyard Stebbins, Francisco J. Ayala
Categories: Medical
Type: BOOK - Published: 2013-04-17 - Publisher: Springer Science & Business Media

One outstanding question in biology is the problem of devel opment: how the genetic instructions encoded in the DNA become expressed in the morphological, physiological, and behavioral features of multicellular organisms, through an ordered sequence of events that extend from the first cell division of the zygote to the adult